Materials in Medicine
We are part of the division of Applied Materials Science, Department of Engineering Sciences, located at the Ångström Laboratory. The MiM group was established in 2005 and is headed by Prof. Håkan Engqvist.
Welcome to the MiM group's website
Our research focuses on the interaction between synthetic materials and living tissues. We seek to understand this interaction and use it to develop biomaterials for medical devices and drug delivery systems. Our group is formed by a multidisciplinary staff with backgrounds in materials science, chemistry, and biotechnology. We conduct applied research in close collaboration with both industry and clinicians at the national and international level.
News
- 100th anniversary of the Royal Swedish Academy of Engineering Sciences 2020-01-09
- Innovation will improve care for chronic pain 2020-04-22
- Innovation price to Håkan Engqvist 2020-01-09
- MiM at the ESB conference 2017 2020-01-09
- PhD defence Michael Pujari-Palmer 2020-01-09
- Uppsala Biomaterials Meeting: November 21st 2020-01-09
- Upptech – A new centre for technology in Uppsala 2020-01-09
- MiM at CMBEE 2018 in Lisbon 2020-01-09
- Jun Luo PhD dissertation 2020-01-09
- The American Ceramic Society: "Gain a winning smile with glass-ceramics" 2020-01-09
MiM Publications
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Bone without borders - Monetite-based calcium phosphate guides bone formation beyond the skeletal envelope
2023
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Combining good mechanical properties and high translucency in yttrium-doped ZrO2-SiO2 nanocrystalline glass-ceramics
2022
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A combined experimental and numerical method to estimate the elastic modulus of single trabeculae
2022
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Monocytes and pyrophosphate promote mesenchymal stem cell viability and early osteogenic differentiation
2022
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Doping of tantalum, niobium, and hafnium in a translucent ZrO2-SiO2 nanocrystalline glass-ceramic
2022
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Effects of dopants with various valences on densification behavior and phase composition of a ZrO2-SiO2 nanocrystalline glass-ceramic
2022
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Experimental Characterization and Mathematical Modeling of the Adsorption of Proteins and Cells on Biomimetic Hydroxyapatite
2022
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Understanding microstructure-mechanical properties relationship in ZrO2-SiO2 nanocrystalline glass-ceramics: The effect of ZrO2 content
2022
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The Influence of Residuals Combining Temperature and Reaction Time on Calcium Phosphate Transformation in a Precipitation Process
2022
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Cytocompatibility and Bioactive Ion Release Profiles of Phosphoserine Bone Adhesive: Bridge from In Vitro to In Vivo
2022
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1-Year pullout strength and degradation of ultrasound welded vs tapped craniomaxillofacial fixation screws
2022
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Magnetic metal-organic frameworks for efficient removal of cadmium(II), and lead(II) from aqueous solution
2022
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Additively manufactured mesh-type titanium structures for cranial implants: E-PBF vs. L-PBF
2021
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Guided bone tissue regeneration using a hollow calcium phosphate based implant in a critical size rabbit radius defect
2021
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Functional properties of low-modulus PMMA bone cements containing linoleic acid
2021
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Titanium reinforced calcium phosphate improves bone formation and osteointegration in ovine calvaria defects: a comparative 52 weeks study
2021
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Sequential macrophage transition facilitates endogenous bone regeneration induced by Zn-doped porous microcrystalline bioactive glass
2021
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Propranolol Reduces the Development of Lesions and Rescues Barrier Function in Cerebral Cavernous Malformations: A Preclinical Study
2021
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Injectable tricalcium phosphate/calcium sulfate granule enhances bone repair by reversible setting reaction
2021
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Characteristics of in vitro infection of human monocytes, by Rickettsia helvetica
2021
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Long-term mechanical properties of a novel low-modulus bone cement for the treatment of osteoporotic vertebral compression fractures
2021
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Size-driven phase transformation and microstructure evolution of ZrO2 nanocrystallites associated with thermal treatments
2021
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A microfluidics-based method for culturing osteoblasts on biomimetic hydroxyapatite
2021
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Comparative study of technologies for tubule occlusion and treatment of dentin hypersensitivity
2021
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Monetite-based composite cranial implants demonstrate long-term clinical volumetric balance by concomitant bone formation and degradation
2021
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Max Phases as Nanolaminate Materials: Chemical Composition, Microstructure, Synthesis, Properties and Applications
2021
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Fabrication and characterization of bioactive zirconia-based nanocrystalline glass-ceramics for dental abutment
2021
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Three-Dimensional Insights into Interfacial Segregation at the Atomic Scale in a Nanocrystalline Glass-Ceramic
2021
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The broad role of Nkx3.2 in the development of the zebrafish axial skeleton
2021
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Oral administration of zolpidem tartrate in an abuse-deterrent formulation versus an immediate release formulation in beagle dogs
2021
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Silk fibroin hydrogels induced and reinforced by acidic calcium phosphate: A simple way of producing bioactive and drug-loadable composites for biomedical applications
2021
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The use of heat to deliver fentanyl via pulmonary drug delivery
2021
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Gluing Living Bone Using a Biomimetic Bioadhesive: From Initial Cut to Final Healing
2021
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Entrapment of a Cytotoxic Drug into the Crystal Structure of Calcite for Targeted Drug Delivery
2021
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Density and mechanical properties of vertebral trabecular bone-A review
2021
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Microstructures and mechanical properties of Al2O3/YAG:Ce3+ eutectics with different Ce3+ concentrations grown by HDS method
2020
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In vivo safety assessment of a bio-inspired bone adhesive
2020
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Synthesis of Phospho-Amino Acid Analogues as Tissue Adhesive Cement Additives
2020
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Glass-Ceramics in Dentistry: A Review
2020
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Enhancement of osteoblast cells osteogenic differentiation and bone regeneration by hydroxyapatite/phosphoester modified poly(amino acid)
2020
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Mechanical behaviour of composite calcium phosphate-titanium cranial implants: Effects of loading rate and design
2020
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The effect of N, C, Cr, and Nb content on silicon nitride coatings for joint applications
2020
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Quantitative phase analyses of biomedical pyrophosphate-bearing monetite and brushite cements by solid-state NMR and powder XRD
2020
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PDMS leaching and its implications for on-chip studies focusing on bone regeneration applications
2020
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The effect of two types of resorbable augmentation materials - a cement and an adhesive - on the screw pullout pullout resistance in human trabecular bone
2020
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Solid-State NMR Rationalizes the Bone-Adhesive Properties of Serine- and Phosphoserine-Bearing Calcium Phosphate Cements by Unveiling Their Organic/Inorganic Interface
2020
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Implicit and explicit finite element models predict the mechanical response of calcium phosphate-titanium cranial implants
2020
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In situ bone regeneration of large cranial defects using synthetic ceramic implants with a tailored composition and design
2020
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Injectable and assembled 3D solid structure for free-to-fixed shape in bone reconstruction
2020
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Calcium and Silicon Delivery to Artificial and Human Nails from Nail Polish Formulations
2020
Popular science

Håkan Engqvist and Wei Xia were interviewed by the Swedish TV: New material should provide better and stronger dentures
Click here to watch the news report
PhD Alumni
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Lewin, Susanne
Functional Aspects of Cranial Implants: Mechanical and Regenerative Properties
2020
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Fowler, Lee
Development of titanium-copper alloys for dental applications
2019
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Janson, Oscar
Bioactive Coatings and Antibacterial Approaches for Titanium Medical Implants
2018
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Fu, Le
Spark plasma sintered ZrO2-SiO2 glass ceramics and Si3N4 bioceramics
2018
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Luo, Jun
Calcium Phosphate Based Biomaterials for Bone Augmentation
2018
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Robo, Céline
Bone-compliant cements for vertebral augmentation
2018
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Pujari-Palmer, Michael
The biological and physical performance of high strength dicalcium phosphate cement in physiologically relevant models
2017
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Ajaxon, Ingrid
Can Bone Void Fillers Carry Load?: Behaviour of Calcium Phosphate Cements Under Different Loading Scenarios
2017
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Chen, Song
Glass Ionomer Cements with Improved Bioactive and Antibacterial Properties
2016
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Pujari-Palmer, Shiuli
Nanofeatures of Biomaterials and their Impact on the Inflammatory Response
2016
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Unosson, Erik
Antibacterial Strategies for Titanium Biomaterials
2015
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Pettersson, Maria
Silicon nitride for total hip replacements
2015
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Cai, Bing
Ceramic Materials for Administration of Potent Drugs
2015
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Montazerolghaem, Maryam
Additives Increasing the Bone-Forming Potential around Calcium Phosphate Cements: Statin, Strontium and Silicon
2015
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Unosson, Johanna
Physical Properties of Acidic Calcium Phosphate Cements
2014
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López, Alejandro
Injectable Biomaterials for Spinal Applications
2014
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Lilja, Mirjam
Bioactive Surgical Implant Coatings with Optional Antibacterial Function
2013
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Lindahl, Carl
Biomimetic Deposition of Hydroxyapatite on Titanium Implant Materials
2012
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Grandfield, Kathryn
Nanoscale Osseointegration: Characterization of Biomaterials and their Interfaces with Electron Tomography
2012
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Åberg, Jonas
Premixed Acidic Calcium Phosphate Cements
2012
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Olofsson, Johanna
Friction and Wear Mechanisms of Ceramic Surfaces: With Applications to Micro Motors and Hip Joint Replacements
2011
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Forsgren, Johan
Functional Ceramics in Biomedical Applications: On the Use of Ceramics for Controlled Drug Release and Targeted Cell Stimulation
2010